Repeated Doses of Drugs
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics of repeated doses of misoprostol.
BACKGROUND Misoprostol is widely used in obstetrics and gynaecology for medical abortion, cervical priming and induction of labour. To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or sublingual administration of repeated doses of 400 microg of misoprostol. METHODS Women undergoing termination of pregnancy by suction evacu...
متن کاملHepatic Oxidative Damages and Glucose Tolerance in Diabetic Rats Exposed to Repeated Oral Doses of Diazinon
Background: Environmental pollutants including organophosphate insecticides impair glucose metabolism by altering hepatic oxidation and play an important role in the development of diabetes and its complications. The aim of this study was to assess the impacts of repeated oral doses of Diazinon, an organophosphate insecticide, which is known to impair the glucose metabolism and its tolerance th...
متن کاملEfficacy of repeated doses of diminazene aceturate (Dinazene®) in the treatment of experimental Trypanosoma brucei infection of Albino rats
The efficacy of repeated doses of Dinazene® in Albino rats experimentally infected with Trypanosoma brucei (Gboko strain) was investigated. A total of 30 adult female Albino rats weighing 130-190 g were used for the study. They were assigned to six groups (groups A-F) of five rats each. Groups A-D were infected intraperitoneally with 1.0 × 106 trypanosomes in 400 μL of PBS diluted blood while g...
متن کاملComparison of Memory Impairment and Oxidative Stress Following Single or Repeated Doses Administration of Scopolamine in Rat Hippocampus
Introduction: Scopolamine, a muscarinic cholinergic receptor antagonist, is widely used to induce memory impairment in experimental animals. The present study aims to compare memory impairment and oxidative stress following single and repeated doses administration of scopolamine. Methods: A group of rats received a single shot of scopolamine in different doses (0.5, 1, or 3 mg/kg, IP) 24 hours...
متن کامل[Motives and circumstances of repeated suicidal attempts by taking drugs].
It has been found out that 45% of the Toxicology Clinic patients hospitalized by their suicide attempt had previous suicide attempts. Calculations have shown that there were 76 previous suicide attempts in all and that 48 (63%) among these were not followed by any psychological and/or psychiatric help. The most frequent reason of this was keeping the attempt secret from further environment. Amo...
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ژورنال
عنوان ژورنال: Nature
سال: 1944
ISSN: 0028-0836,1476-4687
DOI: 10.1038/153494a0